Rhodiola rosea
Adaptogen with EMA monograph for fatigue and stress symptoms. Best in the morning.
Why
Rhodiola rosea has been used historically for endurance under fatigue. Trials in mild-to-moderate burnout and stress-related fatigue show modest improvements in self-reported energy and cognitive performance. Useful when stress presents as flat, drained energy more than wired anxiety.
How it works
Rosavins and salidroside modulate monoamine neurotransmitters (serotonin, dopamine, norepinephrine) and reduce cortisol response to acute stress.
Expected onset · 1–2 weeks for fatigue / energy effects
How to take
Dosage
200–400 mg/day of standardized extract (3% rosavins, 1% salidroside).
Timing
Morning, on empty stomach
On the label
Look for SHR-5 or standardized to 3% rosavins, 1% salidroside.
Ideal for
People with stress-related fatigue rather than acute anxiety.
Safety
Evidence
EMA HMPC monograph registers Rhodiola rosea root as a Traditional Herbal Medicinal Product for symptoms of asthenia (fatigue and weakness): traditional-use registration based on consistent reports of modest improvements in stress-related fatigue and cognitive performance across small RCTs.
Where to get it
Shop Rhodiola rosea on AmazonSponsored · As an Amazon Associate, Healicus earns from qualifying purchases.