Peppermint oil
Strongest evidence in the natural-medicine catalogue for IBS.
Why
Strongest evidence in the natural-medicine catalogue for IBS. Multiple meta-analyses confirm benefit for pain and global symptom improvement.
How it works
Menthol blocks calcium influx in intestinal smooth muscle, producing antispasmodic effect. Enteric coating is essential, uncoated formulations release in the stomach and worsen reflux.
Expected onset · Symptom relief often within 2 weeks; standard trial duration is 4–12 weeks
How to take
Dosage
Enteric-coated capsule: 180–225 mg three times daily, taken 30–60 min before meals, for up to 4–12 weeks.
Timing
30–60 min before meals
On the label
Enteric-coated capsules of standardised peppermint oil, not uncoated capsules or tea.
Safety
Evidence
Ingrosso 2022 Aliment Pharmacol Ther network meta-analysis of IBS treatments: enteric-coated peppermint oil ranked among the most effective interventions for global IBS symptoms and abdominal pain, with an NNT of 4, better than most prescription antispasmodics. Enteric coating is essential; uncoated formulations worsen reflux.
Where to get it
Shop Peppermint oil on AmazonSponsored · As an Amazon Associate, Healicus earns from qualifying purchases.