Aged garlic extract
RCT evidence for reducing cold incidence and duration with daily prophylactic use.
Why
RCT evidence for reducing cold incidence and duration with daily prophylactic use. Aged garlic extract is the standardised form.
How it works
Allyl sulphur compounds (S-allyl-cysteine) modulate immune function and lipid metabolism; Cochrane review supports modest cold-incidence reduction with daily prophylactic use.
Expected onset · Used prophylactically; cold-incidence effect emerges over 8–12 weeks of daily use
How to take
Dosage
Aged garlic extract: 2.56 g/day (4 capsules of Kyolic AGE), as used in the Nantz 2012 RCT for cold/flu severity reduction.
Timing
Daily with food
Safety
Evidence
Nantz 2012 Clin Nutr RCT (n=120 adults, 90-day trial): 2.56 g/day aged garlic extract reduced total cold/flu symptoms by 21% and work/school days missed by 58% vs placebo, with measurable enhancement of γδ-T and NK-cell function. Lissiman 2014 Cochrane review on garlic for cold prevention notes a single positive trial and calls for more research.
Where to get it
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