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Zinc lozenges

Cochrane: zinc lozenges started within 24h of cold symptoms shorten duration by ~1.5 days.

Why

Cochrane: zinc lozenges started within 24h of cold symptoms shorten duration by ~1.5 days. Use acetate or gluconate, not citrate.

How it works

Free zinc ions bind ICAM-1 on nasal epithelium, blocking rhinovirus attachment; effect requires direct mucosal contact (lozenge, not capsule).

Expected onset · Acute use only; effect is on shortening cold duration, not preventing it

How to take

Dosage

≥75 mg elemental zinc per day in divided doses, started within 24 h of first symptom, every 2–3 hours while awake, for up to 1 week.

Timing

Acute-illness only, starting within 24h of first symptom

On the label

Zinc acetate or gluconate, ≥75 mg/day total elemental zinc, not zinc citrate or oxide.

Safety

Causes nausea and bad taste in some users. Do not exceed 1 week of high-dose use. Chronic high-dose zinc causes copper deficiency and may impair immune function.

Evidence

At a glance

Singh & Das 2013 Cochrane review: zinc lozenges (≥75 mg/day elemental zinc, started within 24 h of symptom onset) shortened the common cold by ~1 day vs placebo. Trade-off: nausea and bad taste in some users. Effect requires direct mucosal contact, so lozenges only, not capsules.

Where to get it

Shop Zinc lozenges on Amazon

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