Stinging nettle leaf (Urtica dioica folium)
Small RCT signal for allergic rhinitis, distinct from nettle root (which is for BPH).
Why
Stinging nettle leaf (Urtica dioica, folium) is distinct from the root preparation used for BPH. Two small RCTs report symptom reduction in seasonal allergic rhinitis (Mittman 1990, Roschek 2009). The EMA HMPC monograph for nettle leaf covers traditional use for joint pain (rheumatic complaints) rather than allergic rhinitis specifically.
How it works
Histamine and serotonin content (from the fresh plant) may produce paradoxical desensitisation. Carvacrol and tetrahydropalmatine have documented mast-cell-stabilising effects. Lectins modulate inflammatory cytokines.
Expected onset · Acute symptom relief within hours; sustained-use effects over 1–2 weeks
How to take
Dosage
Standardised freeze-dried extract: 300 mg two or three times daily during allergy season. Dried herb tea: 2–4 g as infusion three times daily.
Timing
Throughout the day during symptomatic phase
On the label
'Urtica dioica leaf' or 'nettle leaf', distinct from 'nettle root' for BPH. Freeze-dried preparation preserves the fresh-leaf bioactives better than air-dried.
Ideal for
Adults with seasonal allergic rhinitis exploring botanical adjuncts; people with rheumatic joint pain (the EMA-monograph indication).
Safety
Evidence
Mittman 1990 Planta Med RCT (n=98 allergic rhinitis): 57% of nettle-treated patients rated symptoms moderately or highly effective vs 37% on placebo at 1 week. Single trial; evidence base remains small. EMA monograph covers traditional use for rheumatic complaints rather than allergic rhinitis specifically.
- Mittman, Planta Med 1990, randomized double-blind study of freeze-dried Urtica dioica in the treatment of allergic rhinitis
- Roschek et al., Phytother Res 2009, nettle extract (Urtica dioica) affects key receptors and enzymes associated with allergic rhinitis
- EMA HMPC monograph, Urtica dioica L., U. urens L., folium (Traditional Use)
Where to get it
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