St. John's wort oil (topical)
EMA-monograph red oil maceration for minor wounds, mild sunburn, and muscle-related skin discomfort. Separate from the antidepressant oral use.
Why
St. John's wort macerated oil (the red infused oil of Hypericum perforatum flowering tops in olive or sunflower oil) holds an EMA HMPC monograph at Traditional Use for symptomatic treatment of minor inflammations of the skin (such as sunburn) and as an aid in the healing of minor wounds. The active hyperforin and hypericin are stable in oil maceration. Distinct from the oral antidepressant extract, same plant, different preparation and indication.
How it works
Hyperforin and hypericin in the oil maceration produce anti-inflammatory effects on cyclooxygenase pathways and stimulate fibroblast proliferation. The red colour comes from hypericin photodimers and is a visual marker of correct preparation.
Expected onset · Wound healing over days; sunburn relief acute
How to take
Dosage
Topical oil or ointment: apply 2–3 times daily to affected area for up to 2 weeks.
Timing
Several times daily during the symptomatic phase
On the label
Macerated oil of Hypericum perforatum flowering tops, should be deep red colour. Olive oil or sunflower oil base. Distinct from St John's wort tincture or dry extract (for oral antidepressant use).
Ideal for
Adults with minor abrasions, mild sunburn, post-procedural skin healing, or muscle-related skin tenderness seeking a traditional topical preparation.
Safety
Evidence
EMA classifies the macerated oil at Traditional Use for minor skin inflammations and minor wound healing. Samadi 2010 RCT (n=144 caesarean-section women): Hypericum oil-treated wounds had significantly better healing scores and lower pain than placebo or routine care at 10 days.
Where to get it
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