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SupplementModerate evidenceStress

Lemon balm

EMA monograph covers traditional use for mild symptoms of mental stress.

Why

EMA monograph covers traditional use for mild symptoms of mental stress. Gentle anxiolytic with RCT support for mood and cognitive performance under stress.

How it works

Rosmarinic acid inhibits GABA transaminase, raising synaptic GABA levels and producing mild anxiolytic effect.

Expected onset · Acute effect within 1–2 hours for subjective calm; cumulative effect over 2–4 weeks

How to take

Dosage

As tea: 1.5–4.5 g of dried leaf in 150 ml hot water, several times daily (EMA). As capsule extract: 300–600 mg standardised extract 1–3 times daily.

Timing

Daytime for stress; evening dose for sleep-supportive use

Safety

Theoretical interaction with thyroid medication and sedatives. Consult a doctor if symptoms persist beyond 2 weeks.

Evidence

At a glance

EMA HMPC monograph registers Melissa officinalis leaf as a Traditional Herbal Medicinal Product for the relief of mild symptoms of mental stress and to aid sleep: traditional-use registration, not full clinical authorisation. Small RCTs report acute anxiolytic and cognitive effects but the modern trial base is thin.

Where to get it

Shop Lemon balm on Amazon

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