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Extra-virgin olive oil

The fat with the strongest cardiovascular evidence. 2–4 tablespoons/day in PREDIMED.

Why

EVOO is the dominant fat in the Mediterranean pattern. Polyphenols (especially oleocanthal) have anti-inflammatory effects. PREDIMED used 4 tablespoons/day and showed cardiovascular event reduction even vs. nut-supplemented Mediterranean diet. Cooking degrades polyphenols somewhat but the fatty-acid profile remains beneficial.

Slot in your day

With a meal

How to do it

How

Use as primary cooking fat and salad dressing. Look for harvest date within the last year. Real EVOO has a peppery throat catch when tasted neat. That's the polyphenols.

Markers this may influence

Evidence

At a glance

Guasch-Ferré 2022 J Am Coll Cardiol (Nurses' Health Study + Health Professionals Follow-up, n=92,383, 28-y follow-up): >½ tablespoon/day olive oil consumers vs never/rarely had 19% lower all-cause and CVD mortality and 29% lower neurodegenerative mortality. PREDIMED used ~4 tablespoons/day with a ~30% major-CVD-event reduction.